Research & Publications

Twin City Heart Foundation Research Projects and Publications

The Twin Cities Heart Foundation (TCHF) Mission is Cardiovascular Research and Education.  The following research projects are ongoing or have been completed by the Twin Cities Heart Foundations.  Publications are also listed below.

TELEMEDICINE AND INFORMATION SYSTEMS: The Twin Cities Heart Foundation continues to assess the role of telemedicine, along with other remote monitoring and information systems, in the evaluation, diagnosis, monitoring and treatment of cardiovascular patients.

The Twin Cities Heart Foundation also continues to evaluate the role that telemedicine (along with other monitoring and information systems) has in allowing the elderly cardiovascular patient to adequately care for themselves outside of a nursing home.

The foundation is concentrating on finding cost effective methods that family members can use to remotely monitor individuals in their family (typically their parents or siblings) thus avoiding the need for assisted living or nursing home placement.

NON-SURGICAL TREATMENT OF VALVULAR HEART DISEASE

The Twin Cities Heart Foundation is collaborating with Dr Pedersen at the Minneapolis Heart Institute evaluating patients with valvular heart disease.  This work has led to numerous national presentations and publications.

PUBLIC HEALTH RISK OF MEDICAL DEVICES AND DRUGS:  The Twin Cities Heart Foundation continues to evaluate the public heart risk and cost due to cardiac complications from medical devices and drugs.

PUBLICATIONS:

1)    Wes R. Pedersen*, Irvin F. Goldenberg*, Itsik Ben-Dor, Ted E. Feldman Aortic and Pulmonic Balloon Valvuloplasty.  Book Chapter.  Aortic Valve Disease.  Editor Ted Feldman

2)    Wes R. Pedersen*,  Irvin F. Goldenberg*, Christopher W. Pedersen,  John R. Lesser, Kevin M. Harris, David S. Feldman,  Björn P. Flygenring, Jonathan Schwartz, Marc R. Pritzker,  Robert S. Schwartz.  Balloon Aortic Valvuloplasty In High Risk Aortic Stenosis Patients With Left Ventricular Ejection Fractions < 20%: A Potential Role For Bridging Valvuloplasty.  Submitted for publication 2012

3)    Wes Pedersen*, Vib Kshetry, Kevin Harris, Robert Hauser, Ben Sun, Irvin Goldenberg*.  Percutaneously treating complex valve disease. Minnesota Physicians February 2011;  22-27

4)    Wesley Pedersen*, Dean Krueger, Mary Dang, Robert Schwartz, Christopher Pedersen, Anil Poulose, Ivan Chavez, Timothy Henry, Irvin Goldenberg*. Incidence of atrioventricular conduction abnormalities following aortic valvuloplasty. Presented and published at the Society for Cardiovascular Angiography and Intervention (SCAI) 2011 Scientific Sessions.

5)    Wesley Pedersen*, Mary Dang, Dean Krueger, Christopher Pedersen, Michael Mooney, Anil Poulose, Timothy Henry, Robert Schwartz, Irvin Goldenberg*. Intra and post procedure outcomes in severe aortic stenosis patients with left ventricular ejection fractions < 20% undergoing balloon vavluloplasty. Presented and published at the Society for Cardiovascular Angiography and Intervention (SCAI) 2011 Scientific Sessions.

6)    Wesley Pedersen*, Dean Krueger, Mary Dang, Robert Schwartz, Christopher Pedersen, Anil Poulose, Ivan Chavez, Timothy D Henry, Irvin Goldenberg*. Balloon Aortic Valvuloplasty Results in low Incidence of Atrioventricular Conduction Abnormalities. Accepted for presentation and publication to the Cardiovascular Research Technologies (CRT) 2011 (CRT 2011) Scientific Meetings.

7)    Wesley R Pedersen1,2, Dean Krueger1, Mary Dang2, Robert S Schwartz1, Christopher Pedersen1, Anil Poulose1, Ivan Chavez1, Timothy D Henry1, Irvin Goldenberg2   1Minneapolis Heart Institute Foundation at Abbott Northwestern Hospital, Minneapolis, MN; 2Twin Cities Heart Foundation, Minneapolis, MN Balloon aortic valvuloplasty results in low incidence of atrioventricular conduction abnormalities.  Cardiovascular Revascularization Medicine vol. 12 issue 3 May - June, 2011. p. e26 DOI: 10.1016/j.carrev.2011.04.313. ISSN: 1553-8389. http://www.crtonline.org/abstract.aspx?PAGE_ID=8549

8)    Christopher Pedersen, Mary Dang, Irvin Goldenberg*, Dean Krueger, Michael Mooney, Timothy D Henry, Robert S. Schwartz, Minneapolis Heart Institute Foundation at Abbott Northwestern Hospital, Minneapolis, MN; Twin Cities Heart Foundation, Minneapolis, MN   Procedural and postoperative outcomes following balloon aortic valvuloplasty in severe aortic stenosis patients with left ventricular ejection fractions <20%.  Cardiovascular Revascularization Medicine vol. 12 issue 3 May - June, 2011. p. 192.   DOI: 10.1016/j.carrev.2011.02.009. ISSN: 1553-8389.  and p. e25-e26  DOI: 10.1016/j.carrev.2011.04.311. ISSN: 1553-8389. http://www.crtonline.org/abstract.aspx?PAGE_ID=8547  Also presented at Cardiovascular Research Technologies (CRT) 2011 (CRT 2011) Scientific Meetings.

9)    Wes R. Pedersen*, MD, FACC, FSCAI; Irvin F. Goldenberg*, MD, FACC, FSCAI; and Ted E. Feldman, MD, FESC, FACC, FSCAI  Balloon Aortic Valvuloplasty in the TAVI Era.  A review of current technique and uses in stand-alone, bridging, and predilation settings. Cardiac Interventions Today July/August 2010; 77-84

10)  Pedersen CW, Schwartz RS, Anderson M, Mooney MR, Poulose AK, Olson S, Boisjolie CR, Goldenberg IF*, Henry TD, Pedersen WR*. Probability of improvement in severe left ventricular systolic dysfunction following balloon aortic valvuloplasty for aortic stenosis. Cardiovasc Revasc Med 2009;10:206.

11)  Anderson M, Schwartz RS, Pedersen C, Poulose AK, Mooney MR, Boisjolie CR, Demmer P, Henry TD, Pedersen WR*. Severity of aortic stenosis, not STS score, predicts procedural mortality in elderly patients undergoing balloon aortic valvuloplasty. Cardiovasc Revasc Med 2009;10(3):207,  DOI:10.1016/j.carrev.2009.04.044

12)  Anderson M, Schwartz RS, Pedersen CW, Poulose AK, Mooney MR, Boisjolie CR, Henry TD, Pedersen WR*. Severity of aortic stenosis, not STS score, predicts procedural mortality in elderly patients undergoing balloon aortic valvuloplasty. Catheter Cardiovasc Interv 2009;74:179.

13)  Pedersen WR*. Klaassen PJ. Pedersen CW. Wilson JA. Harris KM. Goldenberg IF*. Poulose AK. Mooney MR. Henry TD. Schwartz RS. Comparison of outcomes in high-risk patients>70 years of age with aortic valvuloplasty and percutaneous coronary intervention versus aortic valvuloplasty alone. American Journal of Cardiology. 101(9):1309-14, 2008 May 1.

14)  Wes R. Pedersen* and Ted E Feldman.  Percutaneous Treatment for FMR(Functional Mitral Regurgitation): A Ventricular Approach.  Transpericardial LV chamber and annulus remodeling for mitral regurgitation with the iCoapsys System.  Cardiac Interventions Today May/June 2008; 60-64

15)  Wes R Pedersen*, Peter Block, Martin Leon, Paul Kramer, Samir Kapadia, Vasilis Babaliaros, Susheel Kodali, E Murat Tuzcu, Ted Feldman Minneapolis Heart Institute Foundation at Abbott Northwestern Hospital, Twin Cities Heart Foundation, Minneapolis Minnesota.  iCoapsys mitral valve repair system: Percutaneous implantation in an animal model. . Catheterization and Cardiovascular Interventions 72:125-131(2008)

16)  Hidehiko Hara, MD; Wesley R. Pedersen*, MD; Elena Ladich, MD; Michael Mooney, MD; Renu Virmani, MD; Masato Nakamura, MD; Ted Feldman, MD; Robert S. Schwartz, MD  Percutaneous Balloon Aortic Valvuloplasty Revisited Time for a Renaissance? Circulation. 2007;115:e334-e338           DOI: 10.1161/CIRCULATIONAHA.106.657098

17)  Pedersen WR*. Klaassen PJ. Boisjolie CR. Pierce TA. Harris KM. Lesser JR. Hara H. Mooney MR. Graham KJ. Kshettry VR. Goldenberg IF* Priztker MR. Van Tassel RA. Schwartz RS. Feasibility of transcatheter intervention for severe aortic stenosis in patients >or=90 years of age: Aortic valvuloplasty revisited. Catheterization & Cardiovascular Interventions. 70(1):149-54, 2007 Jul 1

18)  Pedersen WR*. Van Tassel RA. Pierce TA. Pence DM. Monyak DJ. Kim TH. Harris KM. Knickelbine T. Lesser JR. Madison JD. Mooney MR. Goldenberg IF*. Longe TF. Poulose AK. Graham KJ. Nelson RR. Pritzker MR. Pagan-Carlo LA. Boisjolie CR. Zenovich AG. Schwartz RS. Radiation following percutaneous balloon aortic valvuloplasty to prevent restenosis (RADAR pilot trial). Catheterization & Cardiovascular Interventions. 68(2):183-92, 2006 Aug

19)  Pedersen WR*, Block P and Feldman T.  The iCoapsys Repair System for the percutaneous treatment of functional mitral insufficiency.  EuroIntervention Supplements (2006) I (Supplement A) A44-A48.

20)  Klaassen PJ, Schwartz RS, Pierce TA, Poulose AK, Boisjolie CR, Mooney MR, Henry TD, VanTassel RA, Pedersen WR*. Combined aortic valvuloplasty and simultaneous coronary stenting in elderly, high risk aortic stenosis patients: the Minneapolis Heart Institute experience. Am J Cardiol 2006;98(8):229M. Presented at the 2006 TCT Meeting.

21)  Pedersen WR*, Mooney MR, Monyak DJ, Pence DM, Kim TH, Harris KM, Pierce TA, Knickelbine T, VanTassel RA, Lesser JR, Madison JD, Boisjolie CR, Nelson RR, Pagan-Carlo LC, Longe TF, Poulose AK, Goldenberg IF*, Schwartz RS. Radiation following percutaneous balloon aortic valvuloplasty to prevent restenosis. (RADAR Pilot): one year follow up. Circulation 2005;112:II-520.

22)  Pedersen WR*, Pence D, Knickelbine T, Pierce T, Van Tassel R, Lesser, Madison J, Harris K, Tae K, Monyak D, Nelson R, Pegan-Carlo L, Longe T, Mooney M,Poulouse A, Goldenberg I*, and Schwartz R.  Minneapolis Heart Institute Foundation/Abbott Northwestern Hospital and Twin Cities Heart Foundation, Minneapolis, MN.  Radiation Following Percutaneous Balloon Aortic Valvuloplasty to Prevent Restenosis (RADAR PILOT). Circulation Supplement III Vol 110, No 17; October 26, 2004; III-440; Abstract # 2072 (Presented at the American Heart Association's Scientific Sessions, November 2004)

23)  Pedersen WR*. Goldenberg IF*. Johnson RK. Mooney MR. Successful rotational atherectomy in the setting of extensive coronary dissection: a case of failed balloon angioplasty in a nondilatable calcified lesion complicated by balloon rupture and extensive dissection. Catheterization & Cardiovascular Interventions. 59(3):329-32, 2003

24)  Pedersen WP*, Goldenberg IF*, Windenburg DC,Carland JL, Traverse JL, Madison JD, Poulose AK, Kim T, Payne JT, Smith J and Mooney MR.  Minneapolis Heart Institute Foundation/Abbott Northwestern Hospital and Twin Cities Heart Foundation, Minneapolis, MN.  The Minneapolis Heart Institute Gamma Coronary Brachtherapy Experience for the Management of Instent Restenosis – A “Real World” Experience in a High Volume Clinical Practice.  SCA&I 2002 Meeting Abstracts. Page 121 Abstract # 40. (The Society for Cardiac Angiography and Interventions 25th Annual Scientific Sessions, May 15-18, 2002.)

 

* Twin Cities Heart Foundation – Co-Authors

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